It only occurred, he says, when the patient was taking another drug called phentermine.
That's what happened in the 1990s with fen-phen, another diet drug combination that includes phentermine.
Unfortunately, unforeseen side effects apparently emerged when Redux and Pondimin were combined with another diet drug, phentermine.
St Albans Crown Court was told Madan sold phentermine and diethylpropion slimming pills at five Easy Slim clinics.
The only FDA-approved weight loss medications are sibutramine (Meridia), orlistat (Xenical), and phentermine.
Redux and Pondimin caused damage to heart valves when used with the diet drug phentermine as part of fen-phen.
The label recommends a daily dose of Qsymia containing 7.5 mg of phentermine and 46 mg of extended-release topiramate.
That combo of two medicines, fenfluramine and phentermine, damaged the heart valves of some of the people who took it.
The drug will also be available at the higher dose of 15 mg of phentermine and 92 mg of extended-release topiramate.
Unfortunately, unforseen side effects emerged sometimes when Redux was combined with another diet drug, phentermine: Patients developed potentially lethal problems with their heart valves.
One of the newly approved drugs, Qsymia, is a combination of phentermine and topirimax, a drug for easing seizures and migraines that also tends to make people feel full.
The US FDA today approved a new weight loss drug that will be called Qsymia, the brand name for the combination of two previously approved drugs, phentermine and extended-release topiramate.
In an email, Astrup said he would support restrictions that would keep lorcaserin and phentermine from being used together until big studies on the safety of the combo had been completed.
Those medications include phentermine and several other stimulants approved for weight loss in the 1950s, as well as drugs to treat diabetes, depression and attention-deficit disorder that have weight-loss as a side effect.
Qsymia's other ingredient is phentermine, an appetite suppressant.
Fenfluramine, the "fen" in fen-phen (the "phen" is phentermine), also stimulates serotonin but in a much broader way, hitting serotonin receptors throughout the body, including a type on the outside of cells near the heart.
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