It was striking that they never brought up EHRs when asked what are the keys to success in improving outcomes for patients with chronic disease.
Aranesp is approved to treat anemia in chemotherapy patients and in anemia patients with chronic kidney disease.
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Although it had been the subject of earlier questions, serious criticism emerged with the publication in 2009 of the TREAT trial, which found no clinical benefit for the drug in patients with chronic kidney disease.
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For example, another study published last month demonstrated that patients with chronic obstructive pulmonary disease were more likely to follow a fitness program using the Nintendo Wii than a traditional fitness program.
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There have been no clinical trials to assess the effect of higher doses, although two other studies done on less-sick patients might suggest the higher doses are problematic--one in 1998 for patients with cardiac disease and one last year for chronic kidney disease patients.
The drug was being tested in patients with stage 4 chronic kidney disease and type 2 diabetes.
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The RED-HF investigators noted that this observation was consistent with an elevated risk for stroke associated with darbepoetin alfa found in the TREAT trial of patients with diabetes, chronic kidney disease, and anemia.
Cachexia is best known as a disease of cancer patients, but it is seen in patients with chronic infection, AIDS, heart failure, rheumatoid diseases and chronic obstructive pulmonary disease.
Children's Hospital at Vanderbilt University, has seen teenage patients with chronic health conditions such as diabetes, congenital heart disease and cystic fibrosis age out of their family's insurance.
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However, if patients living with one lung have diabetes, coronary artery disease, chronic lung disease or are immunosuppressed, they may also be more vulnerable to develop complications such as respiratory distress or failure if they develop an upper respiratory infection such as bronchitis or pneumonia.
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Perhaps the biggest challenge facing health care is to cope with a rise in chronic disease in ways that satisfy increasingly demanding patients without bankrupting national health care systems.
Researchers in the Canadian Network for Observational Drug Effect Studies (CNODES) performed a retrospective observational analysis of administrative databases in Canada, the UK and the US containing more than 2 million patients newly treated with statins. 59, 636 of the subjects already had chronic kidney disease.
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