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Patients with a particular type of lung cancer, called squamous cell carcinoma, were excluded from the trial because a previous study had found that they were more likely than other patients to experience bleeding of the lungs with Avastin therapy.
FORBES: Genentech's Rite Of Spring
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Moreover, he says, the trial excluded patients at high risk for bleeding, such as those with central nervous system tumors or vascular problems.
FORBES: Genentech's Rite Of Spring
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In total, 2, 268 patients who had been referred by their GP to a specialist with symptoms such as rectal bleeding, and increased bowel movements were studied.
BBC: Bowel cancer risk pinpointed
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With Vioxx off the market, arthritis patients have one less choice in how to avoid dying of a bleeding ulcer.
FORBES: Just Say No--to Drug Lawsuits
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The reduction in bleeding translates into a reduction in events and even into a reduction in mortality, particularly in patients with ST-elevation myocardial infarction (STEMI).
FORBES: ESC Gives A Shot In the Arm To Radial Access For PCI Procedures: A New Default?
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It is approved by the U.S. Food and Drug Administration for patients with certain forms of hemophilia or congenital deficiencies in the protein, for whom it can prevent potentially fatal episodes of bleeding.
WSJ: Hemophilia Drug's Off-Label Use Is Faulted