He works with innovators across these groups, drawing them together in his annual Sage Congress around the themes of overcoming health privacy issues and developing open-source methods to which patients, citizens and researchers can contribute.

FORBES: Open-Source Science: The New Norm

And physicians need to talk to their young patients about STIs, risk behaviors and effective prevention methods.

CNN: How sexually active young people can stay safe

Health care providers also have a role to play in ensuring that young people know all their options for family planning, and in providing patients with these methods, the report said.

CNN: Gaps found in young people's sex knowledge

But if his bets on the science and on adopting business methods pay off, the drug industry and millions of patients will benefit.

ECONOMIST: Cancer research

That will be the next step: using genetic tests and other methods of separating those patients who will be helped from those who will not.

FORBES: Magazine Article

Shaw told Case that current methods of assessing pain and agitation in patients were very subjective and often resulted in over-sedation.

CNN: Device to save hospitals billions

Physicians are in a unique position to know what dosages and drug delivery methods work best because they are treating actual patients.

FORBES: Magazine Article

They include high school students (encouraging them to go into social science), doctors (arguing that letting sick, ill-informed patients choose between treatments shirks responsibility) and nonprofits (suggesting they do more experiments assessing whether their methods work).

FORBES: Magazine Article

That leaves patients seeking a heart-health booster beyond statins with old-fashioned lifestyle methods such as diet and exercise.

WSJ: New Rules for Boosting Good Cholesterol

Those papers fail to use double-blind methods to strip out possible researcher bias, and most rely on self-reported mold exposure by patients, many of whom are involved in mold lawsuits.

FORBES: Companies, People, Ideas