Back pain sufferers, even today, are forced to look outside the mainstream for answers from distant experts.
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His position on Middle Eastern matters is so outside the mainstream of both parties that almost no one agrees with him.
In many ways, Bill offers an opinion that is outside the mainstream of venture commentary and simply reflects his own experience.
Saying this puts me well outside the mainstream of most health journalists.
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Bloggers were an unruly lot working outside the mainstream of news reporting.
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Allard, a veterinarian, labeled Strickland a "millionaire-lawyer-lobbyist, " while Strickland attacked Allard as voting outside the mainstream on issues like the environment and health care.
That means Republican leaders run the risk of seeming even more strident, more intolerant, more uncompromising, and more outside the mainstream than they did in 2012.
Outside the mainstream religions--and outside the supervision of the government--are hundreds of independent Chinese religions that gird China like a rural electric network, illuminating lives house by house.
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In so doing, she has given legitimacy to a deeply hostile organization whose goals are far outside the mainstream of both Israeli public opinion and American public opinion.
And while it might make the financial industry more comfortable to portray the protestors as outside the mainstream, they and millions of Americans with the same gripes are having an impact.
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The ILF was established in 1988, but the government decided in 2010 that it had become "no longer appropriate or sustainable" to keep running the scheme outside the mainstream social care system.
The other interesting aspect of the stem-cell link is that it was inspired by work outside the mainstream of the huge cancer-research industry: stem-cell research is now a huge field in its own right.
Just as biotechnology and software have sprung up outside the mainstream drugs and computer industries, so the industry that has grown up on voice circuits will find it hard to transfer its grip to the new world of data networks.
His comments, in prepared testimony at his confirmation hearing, were aimed at defusing claims by some Republicans that Perez's views are outside the mainstream and that his decisions as the government's top civil rights enforcer were often guided by political ideology.
There and elsewhere, Clinton pledged action on many issues that are traditionally Republican -- teenage crime, truancy, illegal immigration, a balanced federal budget and welfare reform -- all the while portraying GOP initiatives on the same issues as extreme and outside the mainstream.
Is this a radical judge outside the conservative mainstream, as some of the Democrats have suggested?
More damaging, however, is the fact that it places him outside of the mainstream in free banking circles and squanders his remaining quasi-libertarian credibility as a champion of markets.
This is especially important for technologies perceived as largely untested or outside of the mainstream.
Online universities were no longer going to be seen as an "alternative", outside of the mainstream, he argued.
"This life" places him far outside the watchmaking mainstream, in a category--independent artisans--all but extinct though now surprisingly vital.
In fact, they could actually save money by bolstering competitiveness and foster greater unity by isolating fringe groups outside the political mainstream.
She relished collaborating with "emerging practitioners and giving them a platform to express work that was outside of the mainstream, " she says.
But Hollings, a fierce critic of industry self-regulation, is outside the bipartisan mainstream, which leans toward enacting mild online privacy legislation, if any.
The FDIC says one in four (28.3%) of all U.S. households conduct some or all of their financial transactions outside of the mainstream banking system.
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The danger is that Hollywood's taste in its own products is becoming as removed from public opinion as its political views are outside the American mainstream.
However, his ideas are still well outside the intellectual mainstream.
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Massachusetts and Texas are both well outside the American mainstream.
That not only provoked calls from Republicans for him to drop out, but also revealed that his total opposition to abortion, however clumsily put, is not outside the Republican mainstream.
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