Engineered in lab mice, this gene produced a protein (named OPG) that vastly increased bone strength and thickness-without causing any harmful side effects.

FORBES: Biotech Behemoth

Amgen researchers stumbled on the OPG gene a decade ago when they found a version of it, oddly enough, in the intestines of rat fetuses.

FORBES: Biotech Behemoth

The OPG research "has paid off spectacularly, " says research czar Perlmutter.

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