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The teams went into the game level on 27 points, with only points difference keeping the Exiles in top spot in the table, and London Irish coach Toby Booth described the game as an "acid test" for his team.
BBC: London Irish 42-12 Gloucester
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Victory took Exeter level on points with second-placed Saracens in the table, with the Chiefs only behind the reigning Premiership champions on points difference.
BBC: Exeter Chiefs 21-11 Wasps
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Saints currently only trail second-placed Warrington on points difference ahead of Saturday's game at Crusaders.
BBC: St Helens prop Bryn Hargreaves has eyes on second spot
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As the difference between the two parties seems to be only 2-3 percentage points, the outcome may be too close to call.
FORBES: Let The Voting Begin
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The Robins, who were only ahead of Cas in the table before the match by virtue of a better points difference, have now moved above city rivals Hull FC to finish in seventh place.
BBC: Hull KR 26-24 Castleford
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Slater takes over as chairman with the club third in League One, only trailing second-placed Sheffield Wednesday on goal difference and leaders Brighton by four points after the two sides battled out a 1-1 draw at the Withdean Stadium on Wednesday.
BBC: Charlton Athletic takeover deal completed
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Still, the difference in 1980 between Sweden and the U.S. is only about four percentage points.
WSJ: Allan Meltzer: A Look at the Global One Percent
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Wolves are now unbeaten in four games and remain third from bottom only by virtue of a one-point goal difference from West Ham, who likewise have 32 points from 30 games.
BBC: Gerard Houllier urges fans to back Aston Villa
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If it is only the difference of a few dollars, try to book with the airlines in one alliance to gather enough points for free flights.
BBC: Insider flight tips from a seasoned business traveller
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He points out that a study comparing a weak cholesterol drug to a powerful one would show no difference if only a few patients were studied, even if the powerful drug was in fact superior.
FORBES: Bristol Prepares Shot In Statin War