Once started, a policy or program is much harder to reform, and sometimes impossible to end.
Once started, infliximab is generally continued as long-term therapy, although its effectiveness may decrease over time.
How many times have you begun a habit only to find that it is difficult to break once started?
Former Michigan coach Lloyd Carr, a high-school assistant before he became a college assistant, said aspiring college coaches once started in high schools and moved up not long afterward.
Bernanke knew that if the economy did slip back into recession, the country ran the risk of entering a deflationary spiral, which once started, is awfully hard to stop.
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Once started, the process is hard to stop.
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But the helicopters and small aircraft from neighbouring Tajikistan and Pakistan that at once started to arrive in Faizabad, carrying medical and other relief supplies to be flown to outlying villages, were soon desperately overstretched.
But none of this necessarily means that thinking has changed enough to keep talks going once started, let alone to produce a settlement to a dispute that has brought about two wars and a 12-year insurgency involving some 35, 000 deaths.
Discouraged by my chart read but not by the underlying story in WPRT, I kept it on the radar and started accumulating shares for a family account once WPRT started tracing higher highs.
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Once Rivera started throwing the pitch in games, it was lights out for opposing hitters.
Once I started reading the case file on the Holloway and Levy cases, I was hooked.
Once I started blogging for Forbes, I got different kinds of responses from different people.
Once authorities started adding the vitamin to milk, rickets, a previously common bone deformity, virtually disappeared.
But NBC couldn't leave them where they were once Idol started its season in January.
Once I started thinking about he world this way, I saw examples all around me.
Once I started to get comfortable with it, I think everything started to roll from there.
As a contrary example, I once inadvertently started a false rumor that company-wide layoffs were looming.
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Happily, to judge from the swarms of users who fled MySpace once Facebook started to catch on.
Once we started using electronic signatures our completion time was reduced to no more than 48 hours.
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Once I started accelerating again, the needle sprang up as the engine quietly came back to life.
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"Once I started the class I saw the benefits of it, " she said.
Once we started representing these companies, we had to deal with cultural disconnects.
Once we started drinking, the conversation at our table became much less impersonal.
Look at Italy and Spain: markets relented once they started reform in earnest.
Once reform started, the People's Insurance Company was separated from the central bank.
Notre Dame had won seven of the previous eight meetings before Sunday night and this one, for once, started slowly.
This shifted the investment on to the suppliers who would only get paid once airlines started paying for the 787s.
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That was easy because I knew once I started I would not be able to stop or just give it up.
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After all, they surely would be tested once Anthony started to face more aggressive defensive strategies designed to slow him down.
"Once she started off the match so fast, she jumped all over me, " added Davenport, who lost the first four games.
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