"Chronic extreme exercise appears to cause excessive 'wear-and-tear' on the heart, " the editorial says.
When you want to kill a snake you have to strike it squarely on the heart.
CNN: ASIANOW - TIME Asia | Young China | The Pen is Nastier Than the Sword--Page 2
Is the setback Merck is facing on the heart drug vorapaxar the fault of Kenneth C.
So do cardiologists, who will be as focused on the heart as rheumatologists are on the joints.
Prof Kivimaki said the evidence of a direct effect of job strain on the heart was mixed.
But there's another question worth asking: Did Merck do enough to study Vioxx's effect on the heart?
Wearing the suits, looking smart and talking about football - no strain on the heart at all.
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But he calls for Bristol-Myers to do a large study to examine the drug's long-term effect on the heart.
The patch is in place to deliver the cells to the appropriate site on the heart and keep them there.
"You're increasing the load on the heart very, very quickly when maybe the heart is not used to it, " he says.
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Despite their findings, Buijsse and his colleagues caution that more research, namely randomized trials on the heart benefits of chocolate, is needed.
And they won it on the heart and grit of Taj McWilliams-Franklin.
If left untreated, kidney damage can worsen and turn into kidney failure, which can have serious affects on the heart, brain, and bones.
Under FitzGerald's hypothesis, Celebrex would have been expected to have the weakest effect on the heart because it is the weakest at inhibiting Cox-2.
"The players have returned home, they'll have spoken to their families and young children and it's a tremendous pull on the heart-strings, " said Gooch.
They will focus constantly on the heart-of-the-matter issues and execute fiercely.
Cannon replies that ibuprofen and naproxen weren't used in his study because they can have other effects on the heart that are not linked to Cox-2.
It will also be possible to check out drugs destined for other parts of the body to see if they have adverse effects on the heart.
Experts advise eating a couple of portions of fish a week, with at least one being an oily fish, because there are proven benefits on the heart.
When people first immerse themselves in such frigid water, their bodies go into "cold shock, " and they start gasping for air, which puts a strain on the heart.
The same chemicals that ease your throat could also lead to insomnia, put more stress on the heart and lead to prostate problems in some men, Overholt said.
Finding out more about the effects of gum disease on the heart would require a massive five- to 10-year-long study using tens of thousands of people, he said.
For after all, If an architect is going to make a mark, well then make an impactful mark on the heart, the soul and the mind of your customers.
Novartis (nyse: NVS - news - people ), which is testing its own Cox-2 drug Prexige, also contends that its drug is safe on the heart.
"Cold weather puts an extra strain on the heart, " the CDC said, also noting that overexertion can become even more dangerous to those with heart conditions in the Arctic cold.
The researchers then gave the DMD mice that had been treated with poloxamer 188 another drug to put stress on the heart and make it work harder and faster for 30 minutes.
Wake Forest's Furberg says further analyses of the data that are now ongoing are only likely to further weaken the claim that there is a delay in Vioxx's affect on the heart.
Exercise elevates heart rate much more than mental stress does, meaning the effects of mental stress on the heart may be caused by adrenaline impacting the heart cells, the study authors said.
At the time the FDA said the drug resulted in "significant" weight loss but the agency said it was concerned about a possible risk of birth defects and an unknown impact on the heart.
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