During that time, astronauts will load about 2, 300 pounds of cargo back on the ship, and then it will return to Earth on March 25, splashing down off the coast of Baja California.

FORBES: SpaceX Struggles, But Remains On Track To Space Station

Based on information provided thus far in the media and a review of the video, a shift in the cargo load seems a likely cause of the accident in my opinion.

FORBES: Deadly 747 Cargo Stall Unlikely In Passenger Airline