And the Premier League side had looked in control until Nevland's red card at the Stadio Olimpico, before going on to lose.
Champions League debutants CFR 1907 Cluj came from behind to beat Roma to record a stunning 2-1 victory at the Stadio Olimpico.
Lazio president Claudio Lotito was disappointed by UEFA's decision, saying it was unfair on the majority of fans at the Stadio Olimpico.
Fulham were behind in the Stadio Olimpico di Torino as early as the ninth minute, when Nicola Legrottaglie headed home from a corner.
The Champions League finals in 2008 and 2009 will be held at the Luzhniki Stadium in Moscow and the Stadio Olimpico in Rome respectively.
Lazio and fellow strugglers Bologna were scoreless at the Stadio Olimpico in Rome while Nicola Amoruso's late penalty earned fifth-placed Parma a 1-1 draw at home to Napoli.
The goal exploded Estadio Olimpico Metropolitano, for the second time.
In May 2011, the ribbon was cut for Ponte della Musica, a pedestrian bridge in the Flaminio district that connects the Stadio Olimpico sports complex with the MAXXI and the Auditorium Parco della Musica.
The final, due to take place at the Stadio Olimpico ground both clubs share, could prove a headache for the authorities after last week's derby between Lazio and Roma was marred by violence, leading to eight arrests.
It was a result that went completely against the form book, with Chelsea arriving at the Stadio Olimpico having gone top of the Premier League at the weekend and Roma on a run of four Serie A defeats.
The film highlighted action images of his players' finest moments - featuring every member of the Barca squad - and Guardiola had clearly done his homework on the Eternal City and Italy ahead of the final in the Stadio Olimpico.
Fulham have rightly won plaudits, and caused plenty of surprises, during their progress in Europe this season but the defensive organisation that has been a hallmark of their displays was absent in the early stages at the Stadio Olimpico di Torino.
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