The on-loan striker then raced on to a neat Jamie O'Hara pass and turned Roger Johnson before slotting home in style.
He saw O'Brien pass his half-century before launching Glenn Rogers out of the ground for the first six of the innings.
BBC: SPORT | Cricket | International Teams | Botha stars as Ireland beat Scots
The European champions jumped out to an early 2-0 lead after Cameroon striker Eto'o chipped a pass to forward Goran Pandev who opened the scoring in the 13th minute.
Soon after play resumed, Hicks scored and then followed a Florida miss with a pass to O.
They looked to have pulled further clear with a marvellous try, but Bowe's final pass to O'Driscoll was correctly ruled forward.
The visitors almost hit back immediately, only for Donncha O'Callaghan to pass forward to Fitzgerald as the full-back burst over the line.
From the back of a scrum, Leinster spread the ball wide with pace and Nacewa was released down the left wing after a neat pass from O'Driscoll.
The incident appeared to spark Wigan into life and they drew level eight minutes from time when Charnley grabbed his second, courtesy of another long pass from O'Loughlin.
Another Munster score soon followed, the forwards driving to suck in the defence before the ball was spun wide to Mafi, who was stopped but popped the pass for O'Leary to shunt over.
Makin's involvement ended 13 minutes from the break when Keith O'Neill's pass out of defence sent Ziege away.
Leinster's bonus point try came when a long pass from Malcolm O'Kelly gave O'Driscoll the space to make the corner again.
BBC: SPORT | Rugby Union | My Club | Leinster | Leinster 26-10 Agen
But they finally scored after 15 minutes when a long pass by Sean O'Loughlin bounced in front of Richards and he passed infield to Carmont to score although Richards missed the extras.
With time running out, the impressive O'Brien burst past Paul Warwick and threw a backhanded pass out of the tackle for the supporting O'Driscoll to run in from the right.
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Lefeimi Mafi raced onto O'Gara's flat pass straight between Flutey and Fraser Waters, and a simple off-load put Tipoki in under the posts, giving O'Gara an easy conversion.
Brough kicked over a drop goal to edge Wakefield ahead again by a single point but Wigan took the lead nine minutes before the break when a delightful inside pass from Leuluai found O'Loughlin.
But with the last move of the opening period, the Scarlets fell behind once more, this time with O'Driscoll's final pass rewarding Fitzgerald's acute angled run and Sexton converted for Leinster to lead 21-8 at the break.
Royal XV skipper Willhelm Koch stretched out for a close-range try before hooker Rayno Barnes rounded off an impressive driving maul to give their side the 15-point margin before O'Gara's inside pass set up wing Tommy Bowe to cross.
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Mr. GERALD FINZI: (Singing, as Page 2) That o'er the green cornfield did pass, in springtime, the only pretty ring time.
The first try came when the Samoan fly-half exhibited his vision by floating a 30-yard pass into space for Connor O'Shea to latch onto.
Ireland have a move where fly-half Jonathan Sexton runs around Brian O'Driscoll to take the return pass on the loop and free the runners out wide.
Lacking stock to use as currency, O'Reilly has been forced to pass on a number of strategic acquisitions for his software division, which makes a Windows-based Web server called WebSite.
With the home side's pack starting to turn the screw, Earls scored Munster's third try in the 47th minute after O'Gara's clever flat pass - although Timoci Nagusa's attempt at a tackle on the winger left a lot to be desired.
There is still no fixed release date for Halo 3 - Mr O'Donnell says the game has to pass the "Bungie test" first.
Kearney ran onto Contepomi's grubber kick down the left wing and slid the ball inside with his boot for O'Driscoll with a pin-point pass Wayne Rooney would have been proud of.
Last weekend, Subash Gurung, 27, who said he was from Nepal, managed to pass through a security checkpoint at O'Hare with seven knives, a stun gun and a box labeled "tear gas" in his carry-on luggage.
After 25 minutes the visitors forced the home side back when O'Donnell took Shaun Lunt's short pass to crash over.
Then came a long pass from makeshift stand-off Sean O'Loughlin to get Charnley over unmarked for his first try on 54 minutes.
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