You know, not irritable, but more directive in a helpful way.

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The reality is that for many illnesses, including not only pain but also minor depression, irritable bowel syndrome, or nausea, the placebos given to patients in clinical trials are pretty fantastic treatments that anybody would choose to take in a heartbeat.

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People who do work more hours tend to become sick more often, are more irritable, less productive, and are not focused.

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In an assessment backed by several of Clarke's colleagues in the Clinton administration, he is described by some in the Bush White House as a "my-way-or-the-highway type, " who can become irritable and difficult to work with if he does not believe his views are being heeded.

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His ideas are not much helped by his writing style, which grows more diffuse and irritable as time goes on.

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Even though the disease is not uncommon, doctors can misinterpret these symptoms and diagnose the patient as suffering from chronic fatigue syndrome and irritable bowel syndrome.

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