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Since the protein needed to transform 5-fluorocytosine could only be churned out by souped-up stem cells, only the gliomas were exposed to the poison, killing them but sparing normal tissue, which the stem cells ignored.
ECONOMIST: Cancer treatment
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Tissue cells, instead of performing the normal self-repair of damaged tissue, begin laying down excessive layers of collagen to help build a scar.
FORBES: Scar Wars
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"We're already using the fact that 5t4 is found in cancer cells, but not in normal tissue, to design immunotherapy against it and are testing two such systems in clinical trials, " said Professor Stern.
BBC: NEWS | Health | Molecule 'helps cancer to spread'