If they seriously want to have any credibility going forward, Dendreon can no longer ask investors to go along for the ride and trust them.

FORBES: What If We've All Been Wrong About Provenge?

But the one question so many otherwise thoughtful people no longer care to ask, among the so many others they entertain, is why Islam.

CENTERFORSECURITYPOLICY: A Campaign of Willful Blindness on Terrorism

And to do that, the manufacturer or service supplier can no longer (as with mass customization) ask for a one-way flow of information from the customer.

FORBES: The Age of Big Data

She doesn't have to ask for a seat belt extender and no longer feels like she's spilling into her neighbor's seat.

CNN: Surgery helps woman drop 135 pounds, 10 dress sizes

To ensure they could no longer flaunt their former access, he added: "I now ask them to destroy and discard all their calling cards and stationery" identifying them as presidential advisers.

CNN: Act II for Estrada

Every five years, we need to ask ourselves, What beliefs and ideas have I accumulated over the last 5 years that are no longer working for me?

FORBES: Why to Clean Your Mindset Like Your Closet