Compounding worries about the Fed was a 7.3% drop in Japan's Nikkei Stock Average.
Japan's Nikkei Stock Average slipped 0.2% as some strengthening in the yen weighed on exporter shares.
In Asia, Japan's Nikkei Stock Average surged 1.9% to its highest level since June 2008.
The softer yen supported Japanese stocks, with the Nikkei Stock Average up 1.2% to 13, 382.89.
Japanese stocks were helped by the weaker yen, with the Nikkei Stock Average up 1.8%.
The Nikkei Stock Average plunged 2.7% to 12220.63, the market's largest percentage decline since May 18.
Japan's Nikkei Stock Average added 1.5% to 8766.36, its highest close since Nov. 7.
Japan's Nikkei Stock Average gained 0.5% to 8336.48 and Taiwan's Taiex added 0.4% to 6662.64.
The Nikkei Stock Average vaulted 3.8% on Wednesday to a four-year high of 11463.75.
Japan's Nikkei Stock Average is 3% higher so far this year, while Korea's Kospi is flat.
Japan's Nikkei Stock Average climbed 1.5% after the Japanese government raised its assessment of the country's economy.
The Nikkei Stock Average was up 1.9% at 13, 574.71 midday after hitting a fresh four-year, nine-month high.
Japan's Nikkei Stock Average fell 1.2% to 13220.07 and South Korea's Kospi Composite lost 1.2% to 1900.06.
Asian exchanges were mixed, with Japan's Nikkei Stock Average falling 0.4% and the Hang Seng gaining 1.6%.
Japan's Nikkei Stock Average gained 0.5% to finish at a 52-week high, up 2.4% for the week.
The Nikkei Stock Average finished down 3.7% at 13, 261.82, a six-week low amid selling by domestic retail investors.
Japan's Nikkei Stock Average rose 0.7%, finishing at a 52-week high, with a 3.6% advance for the week.
In Japan, the Nikkei Stock Average surged 3.6% to a near five-year high, following a long holiday weekend.
Japan's Nikkei Stock Average eased 0.1%, but China's Shanghai Composite added 0.3% to post its seventh consecutive gain.
Japan's Nikkei Stock Average closed down 0.4% after the central bank said it would increase its asset-purchase program.
Japan's Nikkei Stock Average fell 0.5% for a third-straight day, and Hong Kong's Hang Seng Index shed 1%.
Asian markets were mostly higher, with Japan's Nikkei Stock Average rising 0.7% and China's Shanghai Composite adding 0.1%.
Japan's Nikkei Stock Average rose 2.9% to the highest level since January 2008.
Japan's Nikkei Stock Average added 1.1% and Hong Kong's Hang Seng leapt 3.2%.
The softer yen supported Japanese stocks, with the Nikkei Stock Average up 0.9%.
In Tokyo, the Nikkei Stock Average climbed 1.1% to 8, 883.69, a closing level it hasn't seen since Oct. 31.
Asian bourses also finished mostly higher, with Japan's Nikkei Stock Average rising 0.6%.
Asian exchanges also fell, with China's Shanghai Composite ending down 0.6% and Japan's Nikkei Stock Average closing 0.8% lower.
Japan's Nikkei Stock Average lost 1.5% and Hong Kong's Hang Seng fell 2%.
China's Shanghai Composite slid 1.3%, and Japan's Nikkei Stock Average gave up 0.6%.
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