"You're very nervous because we had never seen this before here, " Rodriguez said.
One clinical trial investigator mailed in "before" and "after" X rays of a patient whose tumor vanished after being treated with Iressa, exclaiming that he had never seen this before.
Meanwhile, the position and lighting of "The Bridge of Sighs" (1903-04) suggests we've never before seen this familiar sight.
Which raises a frightening question: What does a show have to do for us to say, "Oh, we've never seen this on reality TV before"?
And we've also heard them say that they've never seen anything like this in Iran before.
International companies are relocating their executives in neighboring countries, and this never-seen-before trend is likely to grow in the coming months.
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"I have never seen it get this high in this area before, " said Bonifay.
"I have never seen the drought like that before, this severe before, " said Newenhouse, who has judged for 23 years.
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It's a story we've seen a thousand times before, but never in this register.
We've seen this story before many times, but it never looked quite like this before.
This comment was a simple acknowledgement that we have seen this movie happen before, and the results never change.
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"This is something we've never seen available for patients before, " said John Miguelez, senior clinical director at Advanced Arm Dynamics, who is not affiliated with Touch Bionics.
"This is really the Lincoln story you've never seen before, " Ridley Scott says.
The Tournaments mode, where players can enjoy playing the classic PAC-MAN with never-before-seen mazes, is a perfect fit for this micro-transaction ecosystem.
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It's interesting to think that he came to southern Iraq as Defense secretary in 1991, but before this trip, he'd never actually seen Baghdad.
"We want people to look through images of the Martian surface - it's a region that's never been explored in this detail before - no one has ever seen these images close up, so we don't know what would be there, " says Dr Lintott.
To support this very dinamic environment, teaching people to think, tackle even problems never seen before.
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One of the merits of this exhibition is that it displays a number of works that have never been seen together before, allowing for comparison and a clear sense of the development of Guardi's increasingly personal style.
When my grandmother died earlier this year, it was the place my relatives posted photos of her I'd never seen before.
Sometimes this involves picking the person who looks the most suspicious, even if we've never seen him before, or being swayed by the subtle hints of police officers and lawyers.
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