• Enbrel, concocted in 1989, targets the prototype member of this gene family: tumor necrosis factor.

    FORBES: Magazine Article

  • Enbrel works by blocking a long-mysterious protein in the immune system known as tumor necrosis factor, or TNF.

    FORBES: Chemical Chameleon

  • These biotech drugs, all of which must be injected, work by binding to a molecule called the tumor necrosis factor.

    FORBES: Drug Giants Gang Up On Rheumatoid Arthritis

  • Thalidomide works, in part, by blocking the production of tumour necrosis factor-alpha, a biochemical which promotes inflammation in the body.

    ECONOMIST: Thalidomide

  • Some tissue death from surgical manipulation, called necrosis, is inevitable after any procedure, though your risks increase dramatically if you're a smoker.

    FORBES: Magazine Article

  • By definition, the surgeon is cutting into those tissues, and if the blood supply is already compromised, necrosis is more likely to occur.

    FORBES: Ten Plastic Surgery Risks You Need To Know

  • Although the two drugs have had success treating arthritis patients, Enbrel and Remicade block only a single cytokine, tumor necrosis factor alpha, leaving dozens of other cytokines untouched.

    FORBES: Blood Works

  • Tumor necrosis factor, named for its ability to make cancer cells die in the test tube, had fizzled in human tests because it was too toxic.

    FORBES: Magazine Article

  • Two days later, a dry necrosis appeared.

    FORBES: Penile Amputation: Nightmare Side Effect

  • CytImmune Sciences of Rockville, Maryland, has just begun a study of the efficacy of Aurimune, a solid-gold nanoparticle that carries a dose of tumour necrosis factor (TNF), a substance that has a natural tendency to stick to gold.

    ECONOMIST: Treating tumours

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