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Levinson is focusing on research into diseases where the immune system goes wrong, like rheumatoid arthritis, multiple sclerosis and allergies.
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The best known examples of this are multiple sclerosis and rheumatoid arthritis.
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Another promising treatment: an anti-CD20 antibody--kind of a second-generation Rituxan--that Genentech plans to test against rheumatoid arthritis, lupus and multiple sclerosis.
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But now, Levinson and Desmond-Hellmann are heading out of their comfort zone into a new field: immunology, which focuses on how the body's own defense systems go awry to cause disorders like rheumatoid arthritis, asthma and multiple sclerosis.
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We now know the SNPs for cancer of the breast, prostate and lung as well as for obesity, diabetes, rheumatoid arthritis, Alzheimer's, multiple sclerosis, cardiovascular disease, deep-vein thrombosis, schizophrenia and countless more.
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Other medicines, including multiple myeloma drug Velcade, from Millennium, and rheumatoid arthritis medicine Enbrel, from Amgen.
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Today monoclonal antibodies are used to treat rheumatoid arthritis, transplant rejection, psoriasis, Crohn's disease, multiple sclerosis, macular degeneration and several types of cancer.
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