Serum shifted from making measles vaccines in small flasks to producing them in larger, more cost-efficient quantities in cell factories.
The problem is not just wheat, but also processed dairy and sugars -- all of which we consume more regularly and in higher quantities than ever before.
Instead, they buy more perishable food in smaller quantities.
That means that drillers must spend ever more money to find ever smaller quantities.
"Bitcoins are really hard to get your hands on if you want to get them in large quantities, " Mr More told the BBC.
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Every year China posts higher economic growth rates, generates dramatically more domestic savings and attracts vastly greater quantities of direct foreign investment.
The savings can be even more with some brands if purchasing in larger quantities.
More modern, more effective chemicals can be used in smaller quantities and are less persistent, so they disappear after a couple of weeks, while heavy metals hang around.
Time and Money are spent in huge quantities in testing and testing and more testing and all that testing is designed to find that last fraction of a percent of an advantage over the competition, so you can win.
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They almost universally do not factor in the other emissions from burning fuel, even though they are more potent, because they exist in much smaller quantities and they also do not persist for centuries as will CO2.
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Building these advanced models will require exploitation of the ensemble of modeling more fully to produce quantitative probabilistic forecasts of atmospheric quantities with estimates of uncertainty to generate probabilistic forecasts of the impacts and risks of weather disasters.
Today's editions, thanks to more durable materials, are likely to survive in large quantities.
Nuclear power offers the possibility of large quantities of baseload electricity that is cleaner than coal, more secure than gas and more reliable than wind.
If a car manufacturer, say, were limited to its home market, it would have a choice between producing small quantities of a number of models and large quantities of just a few, which could be produced more cheaply thanks to economies of scale.
Given recent events, it would appear likely that Avastin, which is typically made in bulk quantities, would be included on such a list and more states will adopt the same policy, especially after the FDA and state health and pharmacy officials hold a scheduled meeting on December 19 to discuss compounding.
The virus used in vaccines is not the actual virus that infects people, but rather a hybrid that's been genetically modified to make it safer, and to give it the ability to multiply more quickly -- a crucial factor when it comes to manufacturing large quantities.
Glaxo's Stephenne hopes to sell huge quantities of malaria vaccine for a modest profit, while using its adjuvant components for more lucrative vaccines, such as one to prevent lung cancer recurrence.
Given the vast quantities of oil being transported around the world each day, there are bound to be more big spills before then.
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