McKay and his colleagues used embryonic stem cells to create a particular type of neuron that can be used to treat a model of Parkinson's disease inmice.
In an in vivo model using severe combined immunodeficient mice, subcutaneous tumors were generated by inoculating the animals with cells from human non-small cell lung carcinoma cell lines.
One model used mice that were implanted with human prostate cancer cells and treated with a drug that is currently in clinical trial for prostate cancer treatment.