Soho House Berlin is housed inside a former 1928 department store in the Mitte District.
Check out the bustling bars of Monbijouplatz or head to Mitte and dance until dawn.
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Rents were cheap in the crumbling tenement blocks in Prenzlauer Berg, Mitte and, later, Friedrichshain.
Rents here can be 600 or 800 Euros a month, whereas in Mitte, a two-bedroom can go for 2, 000 Euro.
But die neue Mitte has had a much lower profile in Germany than the third way has had in Britain.
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"If you're over 35 or have kids, you'll live in Prenzlauer Berg or Mitte, " said Alexander Korte, founder of BerlinInvestment.com, an estate agency.
The massive warehouse in the Mitte district was occupied by artists after the fall of the Berlin Wall and became a major tourist attraction.
The shops themselves come and go but the most interesting boutiques can be found in the boho neighborhoods of Mitte, Prenzlauer Berg and Friedrichshain.
Along with neighbouring Prenzlauer Berg, which has the same late-Victorian apartment blocks and spacious flats, Mitte has been gentrified right out of the urban pioneer's pocket book.
The fashionable Mitte district has a number of classy options, and the huge windows at Newton Bar (Charlottenstrasse 57) offer the opportunity to see as well as be seen.
"Mitte feels a little bit like Soho in New York, " Kimberly Bradley, a journalist who lives there with her partner and daughter and who has spent seven years in Berlin.
Mitte is the most popular, being the first area colonized after the Wall came down, and now the most sought-after place to live for everyone from moneyed ex-pats to the German pied-a-terre buyer.
After the Cold War ended in 1989, artists colonised neighbourhoods such as Mitte and Prenzlauer Berg in eastern Berlin, drawn by the inexpensive rent and enormous, high-ceilinged apartments found in 19th-century buildings and unused department stores.
The Wall Street Journal Deutschland recently held a tech cafe event in the heart of the capital's startup district, Mitte, and much of the talk around the tables of the Kaffeemitte was on German entrepreneurship.
Every pair of glasses is still designed and produced in the latest Mykita Haus in a quiet residential area of Berlin's Mitte district and much of the company's success is based on word-of-mouth, its founders say.
From the viewing platform, visitors are encircled by the 15m-high and 60m-long view, from the neighbourhood of Kreuzberg in the west to the Mitte district in the east, with the iconic spike of the Fernsehturm television tower, smoke-belching factories and dilapidated houses dominating the horizon.
The modern face of Berlin is well represented by the futuristic architecture of Potsdamerplatz , the recently opened Berlin Hauptbahnhof railway station (the biggest two-level station in Europe), the bars and boutiques of the Mitte and Prenzlauer Berg districts and, of course, Berlin's legendary techno clubs.
As artists and students have been gradually priced out of traditional inner-city areas such as Kreuzberg, Friedrichshain, Mitte and Prenzlauer Berg, this southwesterly district has become a haven for the annual hordes of newcomers seeking refuge in its relatively cheap rents, transformed ateliers and bars and burgeoning creative community.
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