Odesnik failed to qualify for this week's Miami Masters after losing in the first round at Indian Wells earlier this month.
Roddick has not played since winning the Miami Masters last month and said the illness had come at just the wrong time.
The Russian fourth seed's last match was a humiliating straight sets loss to veteran Italian Davide Sanguinetti at the Miami Masters in March.
Spain's David Ferrer was a 7-5 6-4 winner over Serbian teenager Novak Djokovic, the sixth seed and winner of the Miami Masters earlier this month.
Federer now has a 102-1 record against players aged over 30 since his 2002 defeat by Andre Agassi in the final of the Miami Masters.
CNN: Champion Federer floors Ferrer to reach semis at ATP finals
Ferrer was playing for the first time since injuring his thigh in the final of the Miami Masters, which he lost to British world No. 3 Andy Murray.
Meanwhile, Venus Williams has been removed from the U.S. squad for their Fed Cup semifinal with Russia due to a knee injury she picked up at the Miami Masters.
Federer, who has not played since the Miami Masters last month, is set to make his return to the circuit at the Rome clay event starting on April 25.
Although Federer had won eight of his previous 10 meetings with Berdych, the Swiss was reduced to tears after losing their first encounter at the Athens Olympics and also succumbed in their most recent duel at April's Miami Masters.
In the meantime, Roddick, who scored a superb victory in the Miami Masters 100 tournament recently, is hoping that Isner and Querrey can step up to the plate to give him some support in the upper echelons of the world game.
Federer -- the man Murray is hoping to eclipse in the world rankings -- as well as Spanish star Rafael Nadal, who won the Indian Wells title on his comeback from injury, have both chosen not to play at the Miami Masters.
Last year, Tomic Junior was booed off court at Wimbledon, picking up a code violation after smashing his racket, as he made a first round exit before then requesting that his father should be ejected from the stands at the Miami Masters later in the year.
Last year, the 20-year-old Tomic was booed off court at Wimbledon, picking up a code violation after smashing his racket, as he made a first round exit before then requesting that his father should be ejected from the stands at the Miami Masters later in the year.
However after playing 18 matches in six weeks, the new world No. 4 has pulled out of next weekend's Miami Masters, though he plans to return for April's Monte Carlo Masters, where he will bid for a ninth successive triumph at the clay court event -- the Mallorcan's favorite surface.
Williams has played just one Fed Cup doubles rubber for the U.S. team and an exhibition match against Serena since withdrawing in New York on August 31, and she will make her return as a wildcard at the Miami Masters this week -- an event she has won on three occasions.
CNN: Will of the Williams: Venus vows to rise again after illness
Also on two under in Miami is 2003 Masters champion Mike Weir.
The men's ATP tour now moves to Miami for another big Masters 1000 event where Britain's Andy Murray will look to defend his title.
Nadal was happy to make it through to final after falling in the last four in his previous Masters events in Miami and Indian Wells.
Djokovic is now aiming to become the first player to win back-to-back ATP Masters 1000 titles in Miami and Monte Carlo, saying he is well prepared for the transition from hard to clay courts.
Ferrer, who had been seeking to become the first Spaniard to win the Miami title, was denied his second Masters-level crown after a demoralizing defeat that means he has yet to beat a top-five player in any of his 37 career finals.
CNN: Murray claims No. 2 ranking with 'brutal' Miami victory
The Czech, seeded 16th, has gone one better than his last-four achievement in Miami last year as he qualified for only his second Masters final.
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