The regimen included three months of insulin injections combined with metformin for all patients.
The second group took the Type 2 diabetes drug metformin twice a day.
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Some patients will be effectively treated with medications such as metformin that increase peripheral sensitivity of organs to insulin.
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Glumetza has grown to become the number one branded generic metformin drug.
Metformin, a cheap generic, has also been shown to prevent diabetes.
It certainly seems worth bringing up this research and asking if Metformin should be added to your treatment regimen in hopes it would slow tumor growth.
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Bristol-Myers Squibb and AstraZeneca announced today that the Food and Drug Administration has approved their diabetes pill Kombiglyze, which combines the diabetes drug Onglyza with metformin, a generic drug.
Clinical trials are currently ongoing to study metformin in early breast cancer treatment and have demonstrated the benefit of metformin in the treatment of prostate, pancreatic, and liver cancer.
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In a 2002 New England Journal of Medicine article, metformin was shown to reduce the progression of pre-diabetes to diabetes by 30%, with the main side effect being gastrointestinal symptoms.
Usually metformin, a basic diabetes medication, is also prescribed.
Novartis hopes that LAF237 combined with metformin will provide patients with more lasting glucose control. (The company is also testing the drug on its own, and will release data on June 8).
At the end of one year, 42 patients on LAF237 plus metformin--a commonly prescribed drug--maintained an A1C level that was on average 1.1% lower than the 29 patients taking metformin and a placebo.
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