The letter will inform physicians that Pradaxa is now contraindicated in patients with mechanical heart valves.

FORBES: Pradaxa To Be Contraindicated In Patients With Mechanical Heart Valves

The misshapen heart is at a mechanical disadvantage, and the heart failure gets worse.

FORBES: Heart Failing? Put A Sock On It

Researchers used to think of heart attacks as being the result of a simple mechanical process, the gradual clogging of the arteries with fatty gunk.

FORBES: Anatomy Of A Heart Attack