In theory, ratings agencies and mathematical models help investors price the risk they are taking on, even if the securities they are buying are scarcely traded.
Even if the engine produced the correct answers, there was still the risk that a transcription or typesetting error would result in the finished mathematical tables being inaccurate.
Mathematical modelling suggests that if microbicides were used by only 20% of women at risk, and were used only half the time, this would still prevent more than 2.5m infections over three years.