Meanwhile, monetary policy remains accomodative but has little chance of making a significant impact on housing, including the latest move by the Federal Reserve.

FORBES: America's Falling Home Sales And Why Bernanke Can't Fix Them

For the past 18 months, I have been speaking publicly about desktop virtualization, and at every conference I keep stressing the inevitability of the smartphone making a significant impact on desktop virtualization.

FORBES: Citrix And The Atrix

Along with a wide television viewership opportunity, March Madness presents advertisers with the possibility of making a significant digital impact.

FORBES: Viewership And Social Media Help March Madness Beat The Super Bowl In Ad Revenue Generation

Most investors will agree that allowing emotion to affect investment decision making can have a significant negative impact on return performance.

FORBES: Know Thyself

Employment lawyer Lisa Mayhew of Berwin Leighton Paisner, said the decision could have "a significant impact on the City" by making female employees more willing to bring equal pay claims to the High Court.

BBC: Birmingham City Council loses equal pay appeal bid

Shadow Home Office minister Diana Johnson said it was "generally accepted that allowing intercept evidence would have a significant impact on some trials, facilitating some prosecutions and making others more likely".

BBC: Mark Duggan