The rise of Tizen will make life more difficult for Microsoft (MSFT) and Research In Motion (RIMM).
On many practical questions, from dealing with traffic police to finding the sugar in a supermarket, not speaking Hebrew can make life more difficult.
While higher interest rates may make life more difficult for those already overburdened with large mortgages, low rates are helping to maintain, and even aggravate, an overvalued property market.
Broadcasters will not deliberately try to make life more difficult for viewers and listeners in the digital age of personal video recorders and IPTV, but they will have to work with content owners who are lobbying hard to protect their copyrighted assets through, for example, automatic expiry on programmes.
More cuts will make life even more difficult.
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If future experiments prove that such genes are essential to the bacterium's happy existence in the gut, then small molecules might be administered to block this pathway and make El Tor's life rather more difficult.
While start-ups are important to job growth and innovation in America, U.S. immigration laws make life for start-up companies much more difficult.
The key now is not to make it even more difficult by making mistakes later in life that are more challenging to overcome.
Life itself can be complicated, so why make it more difficult?
Yet even as rich countries hand out more money with one hand, with the other they continue to make life difficult for the world's poorest by excluding them from rich-country markets.
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