Buyers usually accept this constraint and make the best guess they can.

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The reason for that is that the influenza virus has a rapid rate of mutation, forcing companies that manufacture the vaccine to make their best guess as to which flu types will be more prevalent in a given season.

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And this would be the best official guess we can make.

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For popular connections, such as New York to London or London to Hong Kong, however, there are enough bids to make a pretty fair guess at the best price.

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He said the "best guess" the hospital could make was that the clinical midwife manager in question was Ann Maria Burke and that she had been accompanied by a student midwife.

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Could it that when even conservative banks like Wells Fargo make around two-thirds of their income from trading and derivatives the best minds in the banks are deployed, guess where?

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