But the major modification is that the weapons officer, sitting behind, is concentrating on lining up the next target on the ground.

BBC: News | In Depth | Military Fact Files

Although carbonyl formation is a major oxidative modification induced by peroxynitrite, nitration of tyrosine residues is an indicator of peroxynitrite involvement.

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The two-year-old start-up seeks to combine evidence-based medicine, behavioral modification techniques and smart design to combat major illnesses, such as diabetes, and cardiovascular disease before they become full-blown.

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Now that is important and it isn't just politicians who make that difficult, if I may be so bold, it's also your profession because if a politician says perhaps that's wrong we'll do it slightly differently, your attitude is this is a major and embarrassing u-turn, not actually a sensible modification.

BBC: News Online