Naurex said the mainsideeffects in a Phase IIa study of its GLYX-13 compound with 116 people with depression were headache and sleepiness, similar to the effects of a placebo saline injection.
The clinical trials of the vaccine showed the mainsideeffects being headache and sore arms in a small percent of patients, and those rates were almost exactly the same as those for a sham injection.
Armitage said that the trial results are unlikely to be due to the sideeffects of laropriprant, since the main finding of a lack of benefit is consistent with the AIM-HIGH study and many of the sideeffects are known to be associated with the use of niacin.