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The CHMP was also concerned by liver test results in patients taking Kynamro showing a build-up of fat in the liver and increased enzyme levels, and was not convinced that the company had proposed sufficient measures to prevent the risk of irreversible liver damage.
FORBES: CHMP Recommends Against Approval For Mipomersen In Europe
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In a long-term extension trial one-quarter of mipomersen-treated patients had an average liver fat fraction greater than 20%.
FORBES: FDA Review Raises Safety Concerns About Mipomersen
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Raw whale-meat bacon (a.k.a. blubber) was white, hard to swallow and tasted like pork fat injected with cod-liver oil.
FORBES: Magazine Article
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The balance of protein and carbohydrate and fat -- the cod liver oil.
CNN: 'I stole it from Grandma'
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The process of detoxification allows the liver to convert fat solubles stored in our cells into water-soluble substances that can easily be excreted.
CNN: Dare to detox
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That's because they store fat in their livers (as in cod-liver oil).
CNN: How to buy the best fish
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It is not nearly as powerful as current cholesterol drugs like Merck's Zocor and Pfizer 's (nyse: PFE - news - people ) Lipitor, which work by preventing the liver from turning fat into cholesterol.
FORBES: Magazine Article
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Given by itself, it is less powerful than current cholesterol drugs like Merck's Zocor and Pfizer 's (nyse: PFE - news - people ) Lipitor, which work by preventing the liver from turning fat into cholesterol.
FORBES: Magazine Article
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The decadent sauce is ladled over cheese curd-dotted chips fried in duck fat and topped with 100g of expertly seared goose liver.
BBC: How the Quebecois came to love poutine