The humanitarian problems illustrate the political problem in Zimbabwe, where a power-sharing agreement signed in September between President Robert Mugabe of the ruling ZANU-PF party and MDC leader Morgan Tsvangirai has yet to take effect.

CNN: Cholera deaths rise in Zimbabwe

Mr Barak, the leader of the Labor Party, in effect acts as foreign minister for the peace talks while the man who holds the title, Avigdor Lieberman, has threatened to quit the government if the prime minister gives too much ground.

ECONOMIST: Middle East peace talks

"It's very, very important both from a realistic standpoint and also from perception that this is a stock, this is a company that is a leader, " Mr Kessler says, adding that when a leader falls, it has a definite domino effect.

BBC: Yahoo's next move

Study leader Dana King said he was surprised that the effect was so large and so quick.

BBC: NEWS | Health | Alcohol 'quickly' cuts heart risk

It is not entirely fanciful to speculate that the people of Winchester could in effect start a process which destroys one party leader or another, which makes the by-election one of Professor Crewe's boulders.

ECONOMIST: By-election boulders

Opposition labour leader Anne Western said councillors were "in denial" about the effect of savings on frontline services.

BBC: Derbyshire County Hall

Abilify's side-effect profile is a thorn in the side of market leader Zyprexa, from Eli Lilly (nyse: LLY - news - people ).

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In 2002, there were attempts by the president, Mr Ouattara and the former military leader, Robert Guei to calm things down but this had little effect.

BBC: Central Abidjan

Newport council leader Bob Bright said the expansion and extra jobs could "only have a positive effect on the city".

BBC: South East Wales

He wants Charles Kennedy, the Liberal Democrats' leader, to be able to use the Scottish party's experience of government to good effect at the next British general election.

ECONOMIST: In one part of Britain a Liberal Democrat is in charge