Its lead drug to treat chemotherapy side effects failed, and the Bayer deal yielded nothing fast.
Its lead drug candidate is Flurizan, a therapeutic drug to treat Alzheimer's disease.
Its lead drug candidate will remain Provenge, a vaccine to treat prostate cancer.
In January, Transkaryotic brought its lead drug, Replagal, in front of an advisory panel to the U.S. Food and Drug Administration.
Its lead drug, modafinal, is a widely used treatment for excessive sleepiness that is also awaiting approval for treating ADHD in children.
Its lead drug is only at the earliest stage of human trials.
Millennium Pharmaceuticals has released preliminary results on its lead drug.
That, argues Dr Loew, would deter innovation and lead to drug companies looking for new treatments using rivals' data rather than their own research.
The good news on Neulasta comes on the heels of the submission of palifermin, the lead off drug in Amgen's invigorated research program, to the U.S. Food and Drug Administration.
We also released two reports, one from the Office of the Assistant Secretary for Planning and Evaluation (ASPE) that asses the underlying factors that lead to drug shortages and an FDA report on their role in monitoring, preventing, and responding to these shortages.
But in the meantime, the tax may well lead to higher drug prices and shrinking budgets for finding new drugs.
If implemented, these guidelines could lead to multinational drug companies being forced to sell some medicines at a third of their current prices.
One of the few medical doctors to lead a big drug company, Vasella saw potential in a new leukemia drug called Gleevec when others were skeptical.
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The same firm that loses its lead on one drug might catch up or beat rivals on three others using information gained from a newly transparent process.
And this decision means that big drug companies will have more flexibility to start experimenting with therapies, as long as they can show that down the line the experiments they're doing will lead to a drug that can be marketed.
Find a scientist with a discovery that might lead to a new drug.
Accenture's Mr Bedi is sceptical of the received wisdom that bigger drugs firms will lead to more successful drug discovery.
The findings could lead the Food and Drug Administration to restrict usage only to those 60% of patients without the mutation.
Sirna already has a collaboration with Allergan for its lead compound, a drug to treat age-related macular degeneration, a leading cause of blindness.
He realized, five years before Harvard's Folkman would discover angiostatin, that blocking VEGF with a specially tailored drug might lead to a totally new type of cancer therapy.
Sirna already has a collaboration with Allergan (nyse: AGN - news - people ) for its lead compound, a drug to treat age-related macular degeneration, a leading cause of blindness.
But until now the FDA has focused the bulk of its attention on studies that lead to a new drug's approval and to new marketing claims, not to systematic efforts to pick up new side effects.
While not a huge effect, the results are all but certain to lead to approval of the drug, doctors said.
But news of a delay for Takeda's lead experimental medicine, a drug aimed at lowering cholesterol even more than current blockbusters like Lipitor, Crestor and Vytorin, should worry anyone connected with the drug industry.
In fact, one of the doctors who signed the commentary is Brian Druker, who was the lead academic developer of the drug and is now director of the Knight Cancer Institute at Oregon Health and Science University.
Because most small-molecule drugs can be manufactured with easily replicable chemical processes that lead to a largely reproducible drug formulation, the clinical trial data that supported approval of the original version can be relied upon for the generic versions.
Professor Milner said the research could lead to work on a therapeutic drug within three to five years.
And, as Nathan Sadeghi-Najed noted at TheStreet.com, past failures rightly should lead to skepticism about this new drug.
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Mayor Eberhard van der Laan said banning the sale of the drug to foreigners could lead to more crime.
The concern is that lorcaserin has the potential to cause mind-altering effects that might lead to diversion of the prescription drug for recreational purposes.
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