But I was not prepared for the broad criticism of the companies that took the chance to advance bapi into late stage development.
This productivity surge is supported by the large number of experimental medicines now in late stage development, especially in the area of oncology.
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Oddly, the lethal protein acts somewhat late in development, in skin and muscle cells, and the embryo dies a grisly death unless it carries the antidote.
After its fourth drug failure this year, Merck has two medicines in late-stage development.
Vertex plans to conduct additional studies of VX-661 to further evaluate its potential for late-stage development, pending regulatory discussions.
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Even drugs that have built a strong track record in earlier trials fail in the late stages of development.
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The split ends a decades-long partnership that appeared to unravel after Lilly signed a deal earlier this year with Boehringer Ingelheim to jointly develop and sell several diabetes compounds that are in mid- and late-stage development, including a Boehringer oral diabetes agent known as linagliptin.
In the late 19th century the development of a national stock market enormously increased the value of companies.
The emergence of hardware and software IP load-balancers in the late 1990s catalyzed the development of server-farms by transparently distributing incoming client requests among the servers of a farm.
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But potentially the most interesting development took place late last year when the central authorities gave Newbridge Capital the go-ahead to take a controlling stake in Shenzhen Development Bank.
Hanna's shot at development came in late 1999 when a 28-acre parcel with frontage on Government Camp's main drag surfaced.
The worrying things about the latest delay are that it comes so late in the process of development and that it relates to stresses where the wings join the fuselage.
Various low-level commercial enterprises followed before the fledgling entrepreneur enjoyed his first real success in property development in the late 1960s when he was involved in a project to build Milano Two -- nearly 4, 000 flats -- outside Milan.
Casden Properties opened a 276-unit rental home development in Burbank in late 2010 and is planning to develop an apartment and retail complex in West Hollywood.
They found infants who were fed solids late had no protective effect on the development of these allergies.
By the late 1990s, he had overseen the development of his share of high-profile products, including Intel's Pentium Pro, Pentium II and Pentium MMX processors.
The wave of new drug development in myeloma dates to the late 1990s and early 2000s, when researchers were scouring old treatments for one that might have an impact on the cancer.
The aim is that the development will be open for business in late 2006.
He was working in corporate development for a small conglomerate in the late 1970s when he discovered a company with "a very tidy balance sheet" that happened to be an RV maker.
The development of Sensus Connected Touch gained momentum late in 2011 when Volvo Car Group started sourcing a powerful hardware platform with first-class functional and graphical features and the capacity to handle future expansion.
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Consider how GM indicated late last year that it would be stepping down its development of new conventional hybrids.
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The foundation, named after late entrepreneur Ewing Marion Kauffman, focuses on promoting the development of companies that supporting entrepreneur-friendly policies.
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When BMS was getting ready to start late stage clinical trials, they decided to seek a development and co-marketing partner.
By the late 1970s conversion to a market economy began, including development of export sectors besides the traditional tea and other commodities.
The first few months are fun as product development cranks up in intensity, and many late night discussions ensue on product strategy, customer engagement, fundraising, etc.
They now want the public to have their say on the Draft Buckley Development Brief before it is rubber-stamped in late September.
It also has a drug that is being tested in late-stage clinical trials and another in the early stages of development.
"Malawi is at a crossroads today and action in three to six months may be too late, " said Andrew Mitchell, UK Secretary of State for Development.
James, 22, is a raw talent with huge potential after coming to rugby late from athletics and Wales and Cardiff Blues must persevere with his development.
"We know we've got a good player there - he's come into the game late and he's been out for six months, but his development over the last year has been good, " he said.
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