He said Mezvinsky's mental problems were exacerbated by anti-malaria drug Lariam, which Mezvinsky apparently took on business trips.

CNN: Ex-congressman plans insanity defense in fraud case

It is true that Lariam may very well have had an impact on the precipitation and exacerbation of Mr. Mezvinsky's pre-existing, serious mental illness.

CNN: Ex-congressman plans insanity defense in fraud case

Growing drug resistance and changing climates means that older drugs like chloroquine have become less effective and so new generations of drugs like Lariam have been recommended as frontline preventative treatment.

BBC: The anti-malaria drug dilemma

But it is likely to cost considerably more than Lariam, the controversial anti-malarial treatment produced by their rivals Roche, which has been the focus of numerous health scares because of its potential side effects.

BBC: The anti-malaria drug dilemma

He admits that not only did he fail to take the recommended treatment (Lariam) opting for drugs which were less effective, but he failed to continue taking the tablets on his return to Britain.

BBC: The anti-malaria drug dilemma