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Central defender Ibrahima Sonko, from English second division club Brentford, gets his first call up in the place of Lamine Diatta who is injured.
BBC: Senegal hit by injury
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Eight minutes later, Lamine Diatta, captain in place of injured El Hadji Diouf, made it 3-1 as Mali goalkeeper Mahmadou Sidibe woefully spilled an innocuous Senegalese free-kick.
BBC: CHOOSE A SPORT
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Cisse's injury also leaves the Lions desperately short of cover at centre half: if either Malick Diop or Lamine Diatta gets injured Senegal could be in real difficulty.
BBC: Cisse joins Senegal casualties