Leverkusen won 1-0 at home to Hoffenheim, with striker Stefan Kiessling scoring the only goal in the 67th minute.
The closest Leverkusen came to scoring was when Stefan Kiessling's second-half effort was cleared off the line by Konstantin Rausch.
Tony Kroos' free-kick found Sami Hyypia, who headed into the path of Kiessling and he volleyed home from close range.
But undefeated Leverkusen made no mistake with the Bundesliga top scorer Kiessling leading the way for Jupp Heynckes' men after 22 minutes.
Mario Gomez gave Bayern the lead in the eighth minute, but in-form striker Stefan Kiessling hit back to level six minutes later.
Stefan Kiessling opened the scoring for the home side in the 36th minute and Eren Derdiyok doubled their advantage a minute later.
Kiessling was also unlucky not to get a shot away on Scott Carson's goal after a fine run from another dangerous German break.
Kiessling later had the ball in the net from an offside position and then tested Butt, who had to make a neat save.
Kiessling's equalizer in the 14th minute came as he beat the offside trap before beating Van Buyten and picking his spot beyond Hans-Jorg Butt.
Stefan Kiessling scored the only goal in a 1-0 win for fifth-placed Bayer Leverkusen over Hanover, while Wolfsburg were 3-1 winners over Werder Bremen.
There was still time for Kiessling to miss a glorious chance from five yards but England held on to take a 1-0 lead into Tuesday's second leg in Leverkusen.
Roberto Hilbert shot into the side-netting for the visitors, but Kiessling put the game out of reach on the hour mark, fastening onto another assist from the excellent Kroos to score the third.
However, Stefan Kiessling made it 3-0 after 58 minutes before Zvjezdan Misimovic reduced the deficit with a free-kick on 76 and Grafite's penalty four minutes later, after Hans Sarpei felled Edin Dzeko, set up a tense finish.
Leverkusen made the extra man count and looked to have snatched all three points when a Barnetta cross knocked on by Kiessling and Burak Kaplan's deflected effort looped over Drobny and into the net in the 90th minute.
Jupp Heynckes' side continued to press after the half-time break when Stefan Kiessling saw his shot from the left tipped over the bar by Drobny while Ramos had the ball in the net again for the home side but the effort was chalked off after the assistant referee flagged for offside.
Leverkusen almost took an early lead when Kiessling's goalbound header was blocked by Daniel van Buyten in the fourth minute, but it was Bayern who went ahead soon afterwards as Gomez scored his first goal in over two months from an assist by Miroslav Klose before placing his shot past Rene Adler.
应用推荐