The usual Loki requirements of glibc 2.1 and the 2.2.x series Linux kernel still apply.

CNN: Review: The lowdown on Descent 3 for Linux

By contrast, Windows 7, Vista, OS X Tiger, Leopard, Snow Leopard and versions of the Linux kernel released after September 2009 are all 4K aware.

BBC: Hard drive evolution could hit Microsoft XP users