For a small business, without the resources to fight lengthy legal battles, it is deeply worrying.
It is deeply misleading to omit one of the worst post-war train accidents.
It is deeply unpopular, no political party can possibly advocate it, and none did in the election, including the Pakistan People's Party.
An umbrella group of lawyers has said that it does not accept the dismissal and the Commonwealth has said it is deeply concerned.
But if, to Mr Musharraf and to those abroad, his refusal to adopt mufti is inevitable, to many in Pakistan it is deeply depressing.
It is deeply concerned about who controls the Nile waters, and does not want the creation of a new state on the upper Nile.
The report, from the United Nations Development Fund for Women (Unifem), acknowledges that it is deeply embedded in the history and traditions of many societies.
It is deeply split between technocrat reformists and left-wingers loyal to the memory of Omar Torrijos, an earlier dictator who modernised the country in the 1970s and early 1980s.
And it should not surprise anyone, though it is deeply disappointing, that the Oslo Process that has been constructed, as it were, on Arafat's shoulders, is an unsound exercise.
"It is deeply worrying and sets a dangerous precedent, " he said and advised anyone with a second home in Europe or savings in a European bank to think very carefully.
"It is deeply regrettable that the Thai authorities have yielded to political pressure from outside and carried out this illegal extradition, " Russia's Foreign Ministry said in a statement on Tuesday.
Indeed, it is deeply grateful that Mr Mbeki, and before him Mr Mandela, persuaded the party faithful to ditch their long-held belief in nationalisation and to accept a market economy.
It is deeply regrettable that all those in the executive branch, the Congress and the press who have, over the years, professed such admiration for him now seem so indifferent to his alarms.
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First, it signaled that it is deeply unserious.
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"It is deeply worrying DFID is failing to demand real evidence of the impact of CDC in reducing poverty and that it failed to keep tabs on executive pay, " said shadow international development spokesman Andrew Mitchell.
"It is deeply worrying that after a number of major data losses and the publication of two government reports on high profile breaches of the Data Protection Act, more personal information has been reported lost, " he said.
It is not surprising that MB-associated groups like ISNA, Muslim Advocates or MPAC would be lobbying for the lifting of sanctions against these organizations, but it is deeply disturbing that the U.S. Department of the Treasury would be giving them such insider access to prominent officials to do so.
When it comes to light, the company that commissioned it is usually deeply embarrassed, and tries to disown the investigators it has employed.
Certainly, as preposterous and bedeviling as the system seems, it is also deeply inspiring.
And it is still deeply wounded by the violence of the 1990s.
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Gay lobby group Stonewall says it is "deeply distressed" about the outcome.
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It is a deeply troubled place, one increasingly falling behind its large urban brethren and presenting a host of challenges for new mayor Rahm Emanuel.
It is a deeply affecting film, with a forceful message.
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The UN Security Council showed at an open meeting in New York on Thursday that it is still deeply divided over when and in what cases intervention was justified.
And while whenever there is a so-called green-on-blue incident, it is concerning and the fact that there have been the number of incidents that you mentioned is deeply concerning, it is also important to put it in perspective.
For each, it is who he most deeply is, including his inescapable sexuality.
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