It is a blow to the head or body, which causes a change in brain function.
It is a blow to boss Sanchez who had been looking for a boost from this match against opponents 25 places below them in the world rankings.
It is a fresh blow to Johnson, who is already missing Lewis Moody, Tom Croft, Courtney Lawes and Dave Attwood for at least the first month of the competition.
It is a real blow to those with chaotic and difficult lives who use the services and also those who run them.
It is also a blow to the Women's Tennis Association, which has worked hard to introduce incentives and regulations to reduce the number of withdrawals from its events.
It really is a bitter blow to Bradford and the surrounding area.
"It is a big frustration and disappointment but I don't know how big a blow it is to our title chances, " he stated.
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Worse, if the protection software is cracked straight away, it could deal a fatal blow to what is already an ailing standard.
If DeCSS were to be outlawed, "it would be a blow to Linux development and, because our business is working with this software, it would be a hindrance to our business model, " according to Palvovich.
While the arrival of the iPhone on China Mobile could potentially be a huge blow to China Telecom, it is a good sign that the carrier is not banking on the popular smartphone alone to drive 3G adoption.
It is an early blow to a partnership designed to produce an administration with a working majority.
Like most elevated homes, it is designed to absorb a blow from Mother Nature without jeopardizing either the occupants or diminishing the environment surrounding it.
To convert the businessman into a profiteer is to strike a blow at capitalism, because it destroys the psychological equilibrium which permits the perpetuance of unequal rewards.
If gold is peaking, or in the midst of a parabolic blow-off, it is certainly wise to look for the exits.
It is a necessary but not necessarily sufficient blow to lead to its demise.
You can imagine what a bitter blow it is to me that all my long struggle to win peace has failed.
"This is not some naive, optimistic young man who has inherited a fortune and is about to blow it on some fantasy project on the north coast, " Mr Shaw said.
It is a blow for Dravid, 36, who returned to the side for the lacklustre Champions Trophy campaign in South Africa after a two-year absence.
It is a big blow for Moody, who was hoping to re-establish himself in the England side after missing the autumn internationals following an ankle operation.
We also toured the nearby Tropical Plantation, a lush garden that houses a rich variety of tropical plants, where we learned the proper method of opening a coconut (the secret is a swift blow to the top of the nut, as it can be oriented as if it were a monkey's head).
"When a further rise in borrowing is confirmed by the Office for Budget Responsibility next week, it will be a catastrophic blow to the government's credibility, " he said.
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And though the ruling is a blow to the government, it is hardly likely to be cowed in its pursuit of white-collar criminals.
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And you can react to a blow before the other person knows he is going to punch by watching it start in the tension of the shoulder.
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But there is a very strong likelihood that it would be a fatal blow to the chances of a negotiated settlement with Iran.
No one thinks raising taxes on the middle class is a good idea--it would be a big blow to working families, and it would drag down our entire economy.
It says Mr Sharon is bent on dealing a "death blow" to peace, while the Laborites "may wish to give peace with the Palestinians a chance", by sending a signal they are against settlement expansion.
It is hard to imagine that McChrystal's decision to open his doors to Rolling Stone was a calculated move to blow the lid off of the mirage of strategic competence surrounding the "good war" in Afghanistan.
But it is interesting that in a down economy, Americans are predicted to blow more money on Halloween than ever before.
But, again, the issue is, did you land a sufficiently strong blow that it was going to raise questions among people who seemed to be coalescing around Senator Clinton as the leading Democratic candidate?
If a sizeable number of Labour backbenchers decide to vote against, this will be a blow to Gordon Brown's authority even thought it is not being whipped.
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