In an initial test on 200 insomniacs, it reduced sleeping pill consumption by 40% in five weeks.

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Izzo aptly understands that his players will ultimately need that, so it only makes sense to start early, even as an initial test.

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The iPad is new, and will have a small initial user base, so it makes sense for developers to test the waters with higher-priced apps.

FORBES: Early iPad Apps To Cost Twice As Much As iPhone Apps

Despite the unique research opportunity offered by the volcano, which is now dormant, it has forced the scientist to abandon the initial aim of their expedition to test the normal iron levels in the region.

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For the second type of entrepreneur, Spanos advises them to build a prototype and test it out on potential customers in order to determine whether the initial hypothesis about the opportunity is right or should be changed.

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Last year it said it would scale up its treatment of drug-resistant TB and eventually test all TB patients for resistance at their initial diagnosis.

WSJ: TB Fight Hits a Wall in India