The authors of the PLoS Biology report claimed that iPS cell lines can create live, iPS derived mice that survive into adulthood.
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One iPS cell line was particularly effective: 20 out of 151 embryos yielded adult mice, which were fully composed of iPS derived cells over 90% of the time.
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For example, how will transplanted human iPS cell derivatives behave in terms of cell fate and safety long-term in clinically relevant transplantation settings in rodents or larger animals that are good models for humans?
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The literature on similarities and differences between ES cells and iPS cells, he said, is quite controversial and scientists still do not know whether differences between different iPS cell lines are just due to genetic differences between the adult cell lines that were used for reprogramming or whether genetic changes occurred during reprogramming.
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Now, the Stanford study has shown fat cells can be a player in the quickly evolving area of iPS stem cell research, not because they have their own stem cells but because the fat cells can be turned into iPS cells.
Using in-cell technology, its LCD 4.7-inch IPS HD touchscreen is an impressive 8.4mm slim.
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Opponents of embryonic stem cell research, which involves destroying the donated embryos from which cell lines are derived, have long argued that the discovery of iPS cells in 2006 (for which Shinya Yamanaka was awarded the Nobel Prize in Medicine this past year) obviates the need for embryonic stem cell research.
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Since that time, more advanced cloning technologies have evolved, including the iPS system of induced pluripotent stem cells, which can be grown from nearly any skin cell.
While cloning stem cells is a technical breakthrough, there's already a method of deriving embryonic-like stem cells that doesn't require the use of embryos at all: induced pluripotent stem (IPS) cells, said Dr. George Daley, who is director of the Stem Cell Transplantation Program at Children's Hospital Boston and an international expert in stem cells.
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