Wigan had gone into the interval trailing by six points, despite opening the scoring with an Andy Farrell penalty .
The goal helped Fermanagh lead 1-6 to 0-6 at the interval and three unanswered points after the break extended the home team's lead to six with James Sherry and Adrian Little among the marksmen.
BBC: Mulgrew's Fermanagh are in the last 12 of the Championship
But a fine Richards try, courtesy of a Thomas Leuluai long pass, ensured Wigan trailed by six points at the interval.
It did not get any better for the Scarlets after the interval as James collected 10 points in the space of four minutes.
The Blues were able to survive to the interval without yielding any more points and a well-worked try boosted them early in the second half.
Bearman's lineout catch and pass created sufficient space for Thomas to crash over and Arlidge's conversion and penalty slashed the interval deficit to just six points.
Keys reduced a 16-0 interval deficit to just eight points midway through the second half, but Powell's try killed off the fightback and Williams' second touchdown gave the visitors breathing space.
Monaghan were dealt a major blow with the dismissal of Francis Caulfield in the first half and Queen's upped a gear to lead by two points at the interval at Clones on Saturday afternoon.
Palace wrapped up the points nine minutes after the interval as Ambrose twisted and turned before beating Loach from 18 yards.
Bradford, who gave a Super League debut to 19-year-old Danny Addy, pulled two points back just before the interval with a Sykes penalty.
Giteau's conversion made it 10-0 at the interval, James landing the hosts' first points on the resumption - and their first in 125 minutes of Test rugby - before giving way to Francois Steyn at fly-half after 55 minutes.
The Pumas survived an early Irish onslaught to be 18-10 ahead at the interval and stretched further clear with another Contepomi three points.
After Donnelly's goal helped Tyrone lead by seven, Daniel McLaughlin, Dermot Molloy and Karl Lacey all contributed two points as Donegal moved ahead by the interval.
Blair reduced his side's deficit to three points with a penalty three minutes after the interval but, soon after, Ma'ama Molitika was sin binned for a late and high tackle on Manning.
Irish continued to dominate after the interval with Jarrod Cunningham adding three further penalties to take his match points haul to 16.
Michael J Tierney hit two early points for Laois but Paul McCumiskey's goal and two Timmy Hanna points helped Down lead 1-4 to 0-4 at the interval.
Tomas Cerny denied Motherwell's Tom Hateley from the spot just before the half-time interval after Martin Canning had felled Nick Blackman, but Hamilton held out to take all three points from the narrow victory.
Dermot Molloy and Peter Hughes traded points, before Donegal opened up a 0-7 to 0-3 lead approaching the interval.
After Nacewa missed the conversion, a Steyn penalty cut Leinster's lead to 12 points but a further Nacewa penalty left the Irish province with a 15-point cushion at the interval.
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