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Van Gisbergen, kicking instead of Cipriani, drew Wasps back into it with two penalties of his own and Varndell struck again just before the interval after Wasps stole line-out ball on the Quins 22.
BBC: Wasps 26-15 Harlequins
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And there was no let-up after the interval, the Warriors' line being breached again three more times before the home side ran in three late tries through George Carmont, skipper Sean O'Loughlin and Stefan Marsh.
BBC: Wigan Warriors 28-47 Catalan Dragons
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After the interval, Fulham moved their defensive line further up the pitch and benefited as United's time on the ball was greatly reduced.
BBC: SPORT | Football | Premiership | Fulham 1-1 Man Utd
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But he only survived 10 balls after the interval as Anderson, maintaining an immaculate line and length outside off stump, found the outside edge and Paul Collingwood - retaining the gloves while Matt Prior recovered from a badly-bruised finger - clung on to the catch.
BBC: Anderson inspires England victory
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Cameron Phelps extended their lead after the interval before Joe Westerman and Jordan Turner crossed the line.
BBC: Crusaders 18-58 Hull
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Hibs fell behind early in the game to a wonderful strike from former Easter Road favourite Scott Brown and lost another goal soon after the interval when a Glenn Loovens header crept over the line.
BBC: John Hughes satisfied with Hibernian effort
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The game sprung into life 10 minutes before the interval when Ballack's header was cleared off the line by Kranjcar, while at the other end Portsmouth were unlucky not be given a penalty when Juliano Belletti appeared to handle Baros' attempted flick in the area.
BBC: CHOOSE A SPORT
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Crane gave the Tigers a further boost when he was driven over the line to give Leicester a comfortable 22-3 interval advantage and just after the break Varndell latched on to a Paul Burke chip to put them further ahead.
BBC: Tom Varndell (right) celebrates his try with Sam Vesty