"I haven't seen a single one of these things stick their initial landings or catapult a pre-existing series to new heights, " he said.
Lockett, Robert, and Joseph had still not agreed upon initial capital contributions or their percentage interests in Mariposa.
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In this way, companies, especially startups, can design their products or services to meet the demands of their customer base without requiring large amounts of initial funding or expensive product launches.
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"It's not the first time something in large epidemiological datasets just didn't work out clinically, " Ferris says, noting that statin medications, anti-inflammatory drugs, and estrogen therapy have all failed to live up to their initial promise in preventing or treating Alzheimer's.
Analyzing the trends in content can set the strategic direction for product managers to stick to, or abandon, their initial ideas.
Many times their first impressions were correct, and by taking too long to act on their initial instincts, they made purchases or investments they would have otherwise shied away from.
It goes on to argue that healthcare professionals should use every contact to do this, whatever their area of expertise or the initial purpose of the discussion.
Participating schools pared down their initial lists by eliminating students who received degrees elsewhere or were currently enrolled.
For the carriers, the program is a chance for them to sign up more subscribers and make a small profit, plus more money if customers go over their small initial allotment and need to buy more minutes or text messages.
The biggest newcomers immediately land on the list by way of initial public offerings or spin-offs of major subsidiaries of their former parent companies, who are also on our list.
The deaths at Deepcut, meanwhile, may indeed be suicides, but that does not explain the army's initial reluctance to investigate them or address the bullying which could have been their cause.
In some cases, investors could lose principal, or they may find that low or negative market returns add a big fat zero to their initial deposit.
Oftentimes finding their initial assumptions to be invalid, most of the teams ended up making large or small changes of directions an equal number of times.
If a child responded very well to initial treatment, he or she was much more likely to be doing well in their lives as teenagers than children who didn't respond well.
Researchers cautioned that the report on the baby girl involves just one patient, and the findings appear to have little immediate relevance to people who contract HIV as adults or adolescents and are almost always diagnosed and treated long after their initial infection.
The duo ended up redirecting, or pivoting as would be the correct entrepreneurial-lingo, their initial idea twice, shifting not only customer segment from shopping-averse male college graduates to gay and metrosexual working professionals, but were also forced to realize that their customers did not lack sources of inspiration but needed to be actively sought out.
Gone is the time when a company like TelecomAsia in Bangkok could attract per-share offers of 80 times earnings, or Singapore Telecom at about 35 times earnings, as both did during their initial offerings in 1993.
Rival dealers decried Deutsche's initial response as spivvy, but the case left them uneasy: what if their books were peppered with outdated or confusing names?
They can then leverage their initial investment in a video conferencing platform to add capabilities such as video recording, live video streaming or sharing for additional uses.
"Every CFP worth his or her salt will give the client a no-obligation initial interview, to talk about their goals and objectives, " says Lewis Walker, a Norcross, Ga.
But the initial expression of rage typically comes from people who really do have some fear of a loss of their social position or fear of a loss of their social status because of some change that they see occurring and a change they see as threatening them.
Separating from the pack is increasingly important for travel sites now, as more and more travelers rely on them: According to 2012 travel-consumer statistics compiled by Funsherpa, 87% of travelers used the Internet for a bulk of their trip planning, whether it was to research an upcoming vacation, read online reviews or source initial ideas about where to travel.
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