In osteoporosis the RANK ligand protein is all too effective in producing the breakdown effect, resulting in debilitating hip fractures in postmenopausal women and others.
An understanding of the hormonal nature of breast cancer has led to the development of highly effective treatments for the most common form of breast cancer in postmenopausal women.
FORBES: After 40 Years Of Research, What Do We Know About Preventing Breast Cancer?
Vivus, aiming at surgically menopausal women, found a 64% increase in "satisfying" sexual activity in a small trial of premenopausal women (placebo was 42%) and is now launching a larger late-stage test in postmenopausal women.
The compound may help desire and arousal disorders in postmenopausal women, perhaps by stimulating estrogen receptors at sites in the body, including the brain, says Michael Diamond, an obstetrician and gynecologist at Wayne State University.
It found that hormone therapy, often prescribed to relieve menopausal symptoms and protect against osteoporosis, in healthy postmenopausal women increased the risk of breast cancer, heart disease and stroke.
On Friday the drug was approved for use in combination with Aromasin for postmenopausal women with recurring HER2-negative breast cancer, after treatment with the drugs Femara and Arimidex.
Novartis is conducting a big study to see whether the dug can also prevent relapse in the much bigger group of postmenopausal women with breast cancer.
In the late 1990s many doctors believed postmenopausal women could cut their risk of heart disease by more than half with daily doses of hormones.
The CV event rate and breast cancer rate have been very low to date in subjects at the higher end of CV risk continuum for the intended population of postmenopausal women.
Let's look at one of the biggest changes in medical practice of the past decade: the decision to stop putting millions of postmenopausal women on hormone replacement therapy, which postulated that replacing the estrogen and progesterone their bodies were no longer making would do them long-term good.
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