He set up the Sentebale charity to support orphans and vulnerable children in Lesotho.
The prince is familiar with the hardship that many young people in Lesotho have to face.
The BBC's Peter Biles, in Lesotho, said Harry had become a welcome visitor to Africa's mountain kingdom.
In Lesotho in 1998 and in the Comoro Islands this year, it backed military intervention to restore democracy.
The first phase of the project has been completed with the construction of the Katse dam in Lesotho.
Since 2005, more than 70 teachers from Wales have had placements in Lesotho.
In rural villages in Lesotho, the biggest brick house often belongs not to the chief, but to a miner.
South African lawyer Priti Patel, who was involved in the case, said the ruling was "a dark day for women in Lesotho".
As of 2009, the garment industry in Lesotho provides roughly 40, 000 jobs.
FORBES: Thousands of Jobs Hang On African Textile Trade Deal
In Lesotho, a tiny kingdom encircled by South Africa, textile investors have built 11 new factories and expanded eight others, creating 15, 000 jobs.
At another village in Lesotho a logistical glitch prevented corn seeds donated by an aid organization from arriving in time for the planting season.
He will be accompanied by Prince Seeiso, the younger brother of King Letsie of Lesotho, who first helped to foster Prince Harry's interest in Lesotho.
Eight international construction companies have been charged with bribery in Lesotho after they allegedly paid bribes to win contracts for a multi-million dollar dam project.
And he will stage a fundraising Sentebale Polo Cup match in Connecticut, in aid of his African-based charity, which supports orphans and vulnerable children in Lesotho.
BBC: Prince Harry to tour US to promote troops' rehabilitation
The day which will be marked by speeches and debates by different stakeholders is focusing on the current situation of women and the media in Lesotho.
Next week students and staff from the school in Lesotho will be travelling to spend a week at the Welsh secondary school before a reciprocal exchange next year.
In Lesotho, in a hillside village beset by famine, an old man named Elliot tugged at Fritz's sleeve and took him to see his home, a tiny mud hut.
This will add to an existing 263 Massmart branches across South Africa, 11 in Botswana, 3 in Namibia, 2 in Lesotho and single sites in eight other countries including Nigeria and Uganda.
This debate is necessary because currently, the only time that women are given a platform to voice their issues is when they are victims of rape or any other form of violence in Lesotho.
An ongoing programme with UNESCO is training 10, 000 school principals in Kenya, Ghana, and India, while a second is focusing on training teachers in Lesotho and Kenya to improve STEM education for girls and women.
UNESCO: Detailview | United Nations Educational, Scientific and Cultural Organization
The initiative reinforces an agreement signed earlier this year between UNESCO and GEMS Education to strengthen and promote the advancement of girls in mathematics, science and technology through the training of teachers and school leaders, initially in Lesotho and Kenya.
Pakalitha Mosisili's departure comes after two years of factional squabbles in the Lesotho Congress for Democracy.
BBC: Lesotho's PM Pakalitha Mosisili deserts political party
She will visit the Maelor School in Penley, which is partnered with a school in north Lesotho.
Two huge hydro-electric power schemes, on Lake Cahora Bassa in Mozambique and in the Lesotho mountains, which will zap electricity across the region, are also being built.
This will eventually form part of a water control system comprising at least four other dams and pipelines, controlling rainfall in the Lesotho mountains and supplying fresh water to South Africa.
Kampamba scored the second goal in Zambia's 2-1 win over Lesotho in the quarter-final of the annual southern African championship in June and was the only foreign-based player named in a 20-man squad by Brouwer earlier this week.
Mashaba selected a squad of local players to play Lesotho in Maseru on 8 October.
Harry last visited Lesotho in 2010 when he took his brother, the Duke of Cambridge, to see Sentebale's work.
In Kenya and Lesotho, the Varkey GEMS Foundation works with UNESCO on gender-sensitive teacher training to encourage more girls to attend school and learn science and mathematics.
Whitaker represents Lesotho in the U.S. but no clothing importers.
FORBES: Thousands of Jobs Hang On African Textile Trade Deal
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