Even when no stigma attaches to the drugs involved, most clinical trials end in failure.

ECONOMIST: LSD

Without her bladder functioning properly, she could get urinary sepsis that could damage the organs and end in renal failure.

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Its cost position is so strong that its competitors' attempts to match it on "everyday low prices" end in failure.

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Contrary to Enoch Powell's gloomy crack that all political careers end in failure, Mr Robert's main contention is that Salisbury's was crowned with success.

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Worse was to come, though, so much worse indeed that Mr Weinberger's case may be said to support the dictum that all political careers end in failure.

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MMRF, that most drugmaking will end in failure.

ECONOMIST: REPORTS

Brilliant strategies, badly timed and executed, end up in failure.

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Another woman, in her eighties, with end-stage respiratory and kidney failure, had been in the unit for two weeks.

NEWYORKER: Letting Go

Furthermore, any failure to end the conflict in Darfur could have dire consequences for a longer-running war in southern Sudan and for another in neighbouring Uganda.

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Epogen's main use is to treat anemia in patients with kidney failure, also known as end-stage renal disease.

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An immediate, first-weekend failure would not be the end for Research In Motion.

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And Raikkonen took the final point in eighth place despite retiring with engine failure five laps from the end.

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Wilberforce may have thought that God was punishing him for his failure to end the slave trade: his shame is right there in his gut.

NEWYORKER: Free Spirits