Tests on more than 2, 000 children in several African countries reveal that Lapdap cures significantly more malaria cases than pyri-methamine-sulfadoxine and can help in difficult cases where the latter fails.
In online physician communities such as Sermo and WebMD, doctors can reach out to colleagues for help in difficult cases, and in patient communities such as PatientsLikeMe and CureTogether, patients can share information about their symptoms.
The ability to enumerate business losses is often difficult in privacy cases, which has made it difficult in the past for people to demonstrate they should receive monetary compensation.
They must learn Portuguese, work in often difficult conditions and, in some cases, avoid police raids.
The legal expert from Cambridge University insisted he was not suggesting that the negotiations would be difficult, in most cases.
We came into government in what were obviously controversial circumstances because we are governing with our sworn enemies the Conservative Party, and, even more controversially, we're having to make very, very difficult and in some cases downright unpopular decisions.
And so the difficult job in open cases where there is no clear answer is to take those values in this document, which all Americans hold, which do not change, and to apply them to a world that is ever changing.
''Abandoned cars that are sticking out too far in the street are making snow ploughing difficult in some areas and in some cases making ploughing impossible.
The art and science of medicine is not in picking the easy cases, it is in determining the difficult ones.
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Professor Lord agrees that identifying symptoms is difficult, particularly in severe cases.
But causation is very difficult to attribute in these cases.
As Forbes contributor and veteran Wall Street lawyer Bill Singer points out the defense lawyers on such cases are usually much more experienced than the prosecutors who tend to be younger and have, in many cases, the more difficult job of proving the defendant guilty beyond reasonable doubt.
Under Kurdistan regional governmental laws the site should become a protected area but in reality in many cases those laws are too difficult to implement.
Passionate foodies have long been using online reservation sites like Open Table to quickly check availability at top restaurants, and in some cases, to score otherwise difficult to obtain reservations.
It is has been difficult to prosecute cases of abuse in the ultra-Orthodox community.
In other cases of insider trading it was difficult or impossible to determine the amount of illegal gains.
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It has been difficult to prosecute cases of abuse in the ultra-Orthodox community.
So in essence we have our own local manufacturing and distribution operation that, in some cases, they would have a difficult time matching.
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In many cases, it has become increasingly difficult to accomplish that given the rise in food, fuel and other prices for other essential goods.
In some cases the rescue work was under difficult circumstances.
We have in most cases made the problem bigger and more difficult to solve.
There is no doubt these cases are among the most difficult in the criminal justice system.
Insurers have identified these as one of the main causes of the rapidly rising cost of motor insurance, arguing that in many cases, the claims are fraudulent or too difficult to contest under the present rules.
Dr Kenneth Goodman, an ethics professor at the University of Miami, says that much of the legislation aimed at making it difficult to withdraw care in end-of-life cases had failed to make it onto the statute books.
"It is very difficult to measure pain as it is subjective but in all these cases it is a painful injury, " he said.
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However, the health minister, Earl Howe, feared the move would be "counter-productive" because the concept of integrated care was "difficult to define" and risked being "too narrow" in some cases.
It could prove difficult and costly for an incoming government to turn off the tap in such cases.
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In these places, distances are greater between things, arrangements more logistically difficult, good quality travel information harder to come by, and in some cases, personal safety more of an issue.
In most cases, youths and adults with limited basic literacy skills find it difficult to re-enroll in the formal education system due to family commitments and the fear of being stigmatized.
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